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Titre: Composition and antimicrobial activity of the essential oil of Thymus fontanesii
Auteur(s): Dob, T.
Dahmane, D.
Benabdelkader, T.
Chelghoum, C.
Mots-clés: γ-terpinene
Antimicrobial activity
Essential oil composition
Lamiaceae
Thymol methyl ether
Thymus fontanesii
Date de publication: 2006
Editeur: Pharmaceutical Biology
Collection/Numéro: Volume 44, Issue 8, 1 October 2006;PP. 607-612
Résumé: The yield of oil isolated by hydrodistillation from aerial parts of Thymus fontanesii Boiss. et Reut. (Lamiaceae) growing wild in Djelfa (Algeria) was 0.9%. Analysis of the oil by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS) revealed the identification of 47 components accounting for 98.5% of the total oil. The oil was found to be rich in monoterpenes (91.5%) with major constituents being thymol (29.3%), γ-terpinene (21.7%), p-cymene (15.9%), and thymol methyl ether (11.4%), while a smaller amount of linalool (4.8%) and β-caryophyllene (2.9%) were detected. According to the antimicrobial study using the disk diffusion method and the agar dilution assay-minimal inhibitory concentration (MIC), the oil showed strong in vitro growth inhibition activity against Gram-negative bacteria and antifungal activity. The oil exhibited the maximum antifungal activity against Mucor ramaniamus (MIC = 0.2 μL/mL). © 2006 Informa Healthcare
URI/URL: http://dlibrary.univ-boumerdes.dz:8080/handle/123456789/2213
ISSN: 13880209
Collection(s) :Publications Internationales

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